RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway

RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway

GBM is one of the most malignant tumor in central nervous system. The resistance to temozolomide (TMZ) is inevitable in GBM and the characterization of TMZ resistance seriously hinders clinical treatment. It is worthwhile exploring the underlying mechanism of aggressive invasion and TMZ resistance i...

Full description

Bibliographic Details
Main Authors: Qian Sun, Junjie Xu, Fan’en Yuan, Yan Liu, Qianxue Chen, Lirui Guo, Huimin Dong, Baohui Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Cancer Biology & Therapy
Subjects:
Glioblastoma
RND1
epithelial-mesenchymal transition
AKT
temozolomide
Online Access:https://www.tandfonline.com/doi/10.1080/15384047.2024.2321770

Internet

https://www.tandfonline.com/doi/10.1080/15384047.2024.2321770

Similar Items