TIPE1 inhibits osteosarcoma tumorigenesis and progression by regulating PRMT1 mediated STAT3 arginine methylation

Abstract Osteosarcoma (OS), the most common primary malignancy of the bone, has a poor prognosis due to its high mortality rate and high potential for metastasis. Thus, it is urgently necessary to explore functional molecular targets of therapeutic strategies for osteosarcoma. Here, we reported that...

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Bibliographic Details
Main Authors: Minghao Yang, Yuzhu Zhang, Guangping Liu, Ziqian Zhao, Jigang Li, Le Yang, Kui Liu, Wei Hu, Yunwei Lou, Jie Jiang, Qing Liu, Peiqing Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05273-y