In vitro investigation of the effect of matrix molecules on the behavior of colon cancer cells under the effect of geldanamycin derivative
The chaperone-binding drug, 17-allylamino-17-demethoxygeldanamycin, has recently come into clinical use. It is a derivative of geldanamycin, an ansamycin benzoquinone antibiotic with anti-carcinogenic effect. Understanding the effect of this drug on the cancer cells and their niche is important for...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
IOS Press
2017-10-01
|
Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317720569 |