Dissecting the roles of MBD2 isoforms and domains in regulating NuRD complex function during cellular differentiation

Dissecting the roles of MBD2 isoforms and domains in regulating NuRD complex function during cellular differentiation

Abstract The Nucleosome Remodeling and Deacetylation (NuRD) complex is a crucial regulator of cellular differentiation. Two members of the Methyl-CpG-binding domain (MBD) protein family, MBD2 and MBD3, are known to be integral, but mutually exclusive subunits of the NuRD complex. Several MBD2 and MB...

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Bibliographic Details
Main Authors: Nina Schmolka, Ino D. Karemaker, Richard Cardoso da Silva, Davide C. Recchia, Vincent Spegg, Jahnavi Bhaskaran, Michael Teske, Nathalie P. de Wagenaar, Matthias Altmeyer, Tuncay Baubec
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39551-w

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https://doi.org/10.1038/s41467-023-39551-w

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