A new insight about pharmaceutical dosage forms for benzathine penicillin G.

A new insight about pharmaceutical dosage forms for benzathine penicillin G.

In this work, a micellar system of benzathine penicillin G (BPG) in sodium deoxycholate (NaDC) was developed and evaluated physicochemically. The solubility profile of the drug in water and buffer solutions at various pH was determined, as well as its n-octanol/water partition coefficient. The Criti...

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Bibliographic Details
Main Authors: K. G. HOLANDA E SILVA, F. H. XAVIER-JúNIOR, I. E.G. FARIAS, J. A. CALDAS NETO, A. K.A.S. SILVA, T. NAKASHIMA-JúNIOR, I. B. ARAúJO, A. G. OLIVEIRA, A. C. MEDEIROS, E. S. TABOSA DO EGITO
Format: Article
Language:English
Published: São Paulo State University (UNESP) 2006-01-01
Series:Revista de Ciências Farmacêuticas Básica e Aplicada
Subjects:
benzathine penicillin g; micellar solubilization; micelles; pre-formulation; sodium deoxycholate.
Online Access:http://rcfba.fcfar.unesp.br/index.php/ojs/article/view/571

Internet

http://rcfba.fcfar.unesp.br/index.php/ojs/article/view/571

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