Plasma membrane and nuclear phosphatidylinositol 4,5-bisphosphate signalling in cancer

Plasma membrane and nuclear phosphatidylinositol 4,5-bisphosphate signalling in cancer

Abstract The development of metastasis is a leading cause of cancer-related death that involves specific changes in the plasma membrane (PM) and nucleus of cancer cells. Elevated levels of membrane lipids, including sphingomyelin, cholesterol, and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), i...

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Detalles Bibliográficos
Autores principales: Agnieszka Chytła, Stephanie Rattay, Baki Akgül, Martin Sztacho
Formato: Artículo
Lenguaje:English
Publicado: BMC 2025-02-01
Colección:Lipids in Health and Disease
Materias:
Phosphatidylinositol 4,5-bisphosphate
Nucleus
Biocondensates
Cancer
Metastasis
HPV
Acceso en línea:https://doi.org/10.1186/s12944-025-02452-6

Internet

https://doi.org/10.1186/s12944-025-02452-6

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