Helminth extracellular vesicles co‐opt host monocytes to drive T cell anergy

Helminth extracellular vesicles co‐opt host monocytes to drive T cell anergy

Abstract Parasitic helminths secrete extracellular vesicles (EVs) into their host tissues to modulate immune responses, but the underlying mechanisms are poorly understood. We demonstrate that Ascaris EVs are efficiently internalised by monocytes in human peripheral blood mononuclear cells and incre...

ver descrição completa

Detalhes bibliográficos
Principais autores: Anne Borup, Mohammad Farouq Sharifpour, Litten S. Rossen, Bradley Whitehead, Anders T. Boysen, Rikke Olesen, Anja B. Bohn, Andrea Ridolfi, Marco Brucale, Francesco Valle, Lucia Paolini, Annalisa Radeghieri, Paolo Bergese, Kim Miles, Margaret Veitch, Tamara Thomas, Roland Ruscher, Phurpa Wangchuk, Paul Giacomin, Alex Loukas, Peter Nejsum
Formato: Artigo
Idioma:English
Publicado em: Wiley 2025-01-01
coleção:Journal of Extracellular Vesicles
Assuntos:
Ascaris
colitis
extracellular vesicles
helminth
host‐parasite interaction
immune modulation
Acesso em linha:https://doi.org/10.1002/jev2.70027

Internet

https://doi.org/10.1002/jev2.70027

Registros relacionados