Therapeutic protein PAK restrains the progression of triple negative breast cancer through degrading SREBP-1 mRNA

Therapeutic protein PAK restrains the progression of triple negative breast cancer through degrading SREBP-1 mRNA

Abstract Triple-negative breast cancer (TNBC) represents the most challenging subtype of breast cancer. Studies have implicated an upregulation of lipid synthesis pathways in the initiation and progression of TNBC. Targeting lipid synthesis pathways may be a promising therapeutic strategy for TNBC....

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Bibliographic Details
Main Authors: Pan Hu, Peiyi Zhou, Tieyun Sun, Dingkang Liu, Jun Yin, Lubin Liu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Breast Cancer Research
Subjects:
Therapeutic protein
Lipogenesis
Fatty acid
SREBP-1
Triple negative breast cancer
Online Access:https://doi.org/10.1186/s13058-023-01749-7

Internet

https://doi.org/10.1186/s13058-023-01749-7

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