Therapeutic protein PAK restrains the progression of triple negative breast cancer through degrading SREBP-1 mRNA
Abstract Triple-negative breast cancer (TNBC) represents the most challenging subtype of breast cancer. Studies have implicated an upregulation of lipid synthesis pathways in the initiation and progression of TNBC. Targeting lipid synthesis pathways may be a promising therapeutic strategy for TNBC....
Main Authors: | Pan Hu, Peiyi Zhou, Tieyun Sun, Dingkang Liu, Jun Yin, Lubin Liu |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-12-01
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Series: | Breast Cancer Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13058-023-01749-7 |
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