A simple model of epileptic seizure propagation: Potassium diffusion versus axo-dendritic spread.

The mechanisms of epileptic discharge generation and spread are not yet fully known. A recently proposed simple biophysical model of interictal and ictal discharges, Epileptor-2, reproduces well the main features of neuronal excitation and ionic dynamics during discharge generation. In order to dist...

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Bibliographic Details
Main Authors: Anton V Chizhov, Aleksei E Sanin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0230787