Methylation of p16 ink4a promoter is independent of human papillomavirus DNA physical state: a comparison between cervical pre-neoplastic and neoplastic samples
BACKGROUND Epigenetic modifications in host cells, like p16 ink4a methylation, have been considered as putative complementary mechanisms for cancer development. Because only a small proportion of infected women develop cervical cancer, other factors might be involved in carcinogenesis, either indep...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Fundação Oswaldo Cruz (FIOCRUZ)
2018-12-01
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Series: | Memorias do Instituto Oswaldo Cruz |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100301&lng=en&tlng=en |