Integrative systems biology reveals NKG2A-biased immune responses correlate with protection in infectious disease, autoimmune disease, and cancer

Summary: Infection, autoimmunity, and cancer are principal human health challenges of the 21st century. Often regarded as distinct ends of the immunological spectrum, recent studies hint at potential overlap between these diseases. For example, inflammation can be pathogenic in infection and autoimm...

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Bibliographic Details
Main Authors: Daniel G. Chen, Jingyi Xie, Jongchan Choi, Rachel H. Ng, Rongyu Zhang, Sarah Li, Rick Edmark, Hong Zheng, Ben Solomon, Katie M. Campbell, Egmidio Medina, Antoni Ribas, Purvesh Khatri, Lewis L. Lanier, Philip J. Mease, Jason D. Goldman, Yapeng Su, James R. Heath
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724002006