Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state.

Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state.

In a recent intervention study, the daily supplementation with 200 mg monomeric and oligomeric flavanols (MOF) from grape seeds for 8 weeks revealed a vascular health benefit in male smokers. The objective of the present study was to determine the impact of MOF consumption on the gene expression pro...

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Bibliographic Details
Main Authors: Dragan Milenkovic, Wim Vanden Berghe, Céline Boby, Christine Leroux, Ken Declerck, Katarzyna Szarc vel Szic, Karen Heyninck, Kris Laukens, Martin Bizet, Matthieu Defrance, Sarah Dedeurwaerder, Emilie Calonne, Francois Fuks, Guy Haegeman, Guido R M M Haenen, Aalt Bast, Antje R Weseler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3998980?pdf=render

Internet

http://europepmc.org/articles/PMC3998980?pdf=render

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