A neonatal murine model of coxsackievirus A4 infection for evaluation of vaccines and antiviral drugs

A neonatal murine model of coxsackievirus A4 infection for evaluation of vaccines and antiviral drugs

ABSTRACTCoxsackievirus A4 (CVA4) infection can cause hand, foot and mouth disease (HFMD), an epidemic illness affecting neonatal and paediatric cohorts, which can develop to severe neurological disease with high mortality. In this study, we established the first ICR mouse model of CVA4 infection for...

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Bibliographic Details
Main Authors: Zhenjie Zhang, Xingcheng Zhang, Michael J. Carr, Hong Zhou, Juan Li, Shaoqiong Liu, Tao Liu, Weijia Xing, Weifeng Shi
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
Subjects:
HFMD
coxsackievirus A4
murine model
inactivated vaccine
antiviral drugs
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2019.1673135

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2019.1673135

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