A Feedback Regulatory Loop Containing McdR and WhiB2 Controls Cell Division and DNA Repair in Mycobacteria

A Feedback Regulatory Loop Containing McdR and WhiB2 Controls Cell Division and DNA Repair in Mycobacteria

ABSTRACT Cell division must be coordinated with DNA repair, which is strictly regulated in response to different drugs and environmental stresses in bacteria. However, the mechanisms by which mycobacteria orchestrate these two processes remain largely uncharacterized. Here, we report a regulatory lo...

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Bibliographic Details
Main Authors: Wei Zhou, Shaojia Huang, Bridgette M. Cumming, Yong Zhang, Wei Tang, Adrie J. C. Steyn, Shiyun Chen, Yangbo Hu
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:mBio
Subjects:
Mycobacterium tuberculosis
stress response
drug resistance
transcriptional regulation
Wbl
Rv1830
Online Access:https://journals.asm.org/doi/10.1128/mbio.03343-21

Internet

https://journals.asm.org/doi/10.1128/mbio.03343-21

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