Elevated 17β-estradiol protects females from influenza A virus pathogenesis by suppressing inflammatory responses.
Studies of the 1918 H1N1 influenza pandemic, the H5N1 avian influenza outbreak, and the 2009 H1N1 pandemic illustrate that sex and pregnancy contribute to severe outcome from infection, suggesting a role for sex steroids. To test the hypothesis that the sexes respond differently to influenza, the pa...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-07-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC3145801?pdf=render |