Carbohydrate Metabolism in Bacteria: Alternative Specificities in ADP-Glucose Pyrophosphorylases Open Novel Metabolic Scenarios and Biotechnological Tools

Carbohydrate Metabolism in Bacteria: Alternative Specificities in ADP-Glucose Pyrophosphorylases Open Novel Metabolic Scenarios and Biotechnological Tools

We explored the ability of ADP-glucose pyrophosphorylase (ADP-Glc PPase) from different bacteria to use glucosamine (GlcN) metabolites as a substrate or allosteric effectors. The enzyme from the actinobacteria Kocuria rhizophila exhibited marked and distinctive sensitivity to allosteric activation b...

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Bibliographic Details
Main Authors: Jaina Bhayani, Maria Josefina Iglesias, Romina I. Minen, Antonela E. Cereijo, Miguel A. Ballicora, Alberto A. Iglesias, Matias D. Asencion Diez
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Microbiology
Subjects:
glucose-1-phosphate
glucosamine-1-phosphate
glucosamine-6-phosphate
allosterism
promiscuity
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.867384/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2022.867384/full

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