NF-κB regulation in maternal immunity during normal and IUGR pregnancies

Abstract Intrauterine Growth Restriction (IUGR) is a leading cause of perinatal death with no effective cure, affecting 5–10% pregnancies globally. Suppressed pro-inflammatory Th1/Th17 immunity is necessary for pregnancy success. However, in IUGR, the inflammatory response is enhanced and there is a...

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Bibliographic Details
Main Authors: Gaayathri Ariyakumar, Jonathan M. Morris, Kelly J. McKelvey, Anthony W. Ashton, Sharon A. McCracken
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-00430-3