Genetic determinants of host tropism in Klebsiella phages

Summary: Bacteriophages play key roles in bacterial ecology and evolution and are potential antimicrobials. However, the determinants of phage-host specificity remain elusive. Here, we isolate 46 phages to challenge 138 representative clinical isolates of Klebsiella pneumoniae, a widespread opportun...

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Bibliographic Details
Main Authors: Beatriz Beamud, Neris García-González, Mar Gómez-Ortega, Fernando González-Candelas, Pilar Domingo-Calap, Rafael Sanjuan
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723000591