Expression of factor XIII originating from synovial fibroblasts and macrophages induced by interleukin-6 signaling

Expression of factor XIII originating from synovial fibroblasts and macrophages induced by interleukin-6 signaling

Abstract Background Blood coagulation factor XIII (FXIII) promotes cross-linking between fibrin molecules at the final stage of the blood coagulation cascade. However, its expression in cells or tissues and function, particularly factor XIII subunit B (FXIII-B), remains controversial. Hemorrhagic FX...

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Bibliographic Details
Main Authors: Hirofumi Watanabe, Sho Mokuda, Tadahiro Tokunaga, Hiroki Kohno, Michinori Ishitoku, Kei Araki, Tomohiro Sugimoto, Yusuke Yoshida, Toshihiro Yamamoto, Mayuko Matsumoto, Junya Masumoto, Shintaro Hirata, Eiji Sugiyama
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Inflammation and Regeneration
Subjects:
Rheumatoid arthritis
Blood coagulation factor XIII
Monocyte-derived macrophages
Fibroblast-like synoviocytes (FLS)
Interleukin-6
Online Access:https://doi.org/10.1186/s41232-022-00252-4

Internet

https://doi.org/10.1186/s41232-022-00252-4

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