Candesartan Does Not Activate PPARγ and Its Target Genes in Early Gestation Trophoblasts

Candesartan Does Not Activate PPARγ and Its Target Genes in Early Gestation Trophoblasts

Angiotensin II receptor 1 blockers are commonly used to treat hypertension in women of childbearing age. While the fetotoxic effects of these drugs in the second and third trimesters of pregnancy are well documented, their possible impacts on placenta development in early gestation are unknown. Cand...

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Bibliographic Details
Main Authors: Lena Neuper, Daniel Kummer, Désirée Forstner, Jacqueline Guettler, Nassim Ghaffari-Tabrizi-Wizsy, Cornelius Fischer, Herbert Juch, Olivia Nonn, Martin Gauster
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
candesartan
PPARγ
placenta
trophoblast
first-trimester pregnancy
rosiglitazone
Online Access:https://www.mdpi.com/1422-0067/23/20/12326

Internet

https://www.mdpi.com/1422-0067/23/20/12326

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