Establishment of large canine hepatocyte spheroids by mixing vascular endothelial cells and canine adipose-derived mesenchymal stem cells

Introduction: Differentiation of hepatocytes and culture methods have been investigated in dogs as a tool to establish liver transplant and drug metabolism examination systems. However, mass culture techniques for canine hepatocytes (cHep) have not been investigated, and it is necessary to construct...

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Bibliographic Details
Main Authors: Akito Ichikawa, Sakurako Neo, Ryouhei Nukui, Yoko Yamada, Suguru Nitta, Hidetoshi Iwaki, Yusuke Yanagi, Koichi Nakayama, Shoichi Sato, Satoko Tateishi, Masaharu Hisasue
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Regenerative Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320421000894