Amyloid Fibrils of Stefin B Show Anisotropic Properties

Amyloid Fibrils of Stefin B Show Anisotropic Properties

Human stefin B, a member of the cystatin family of cysteine protease inhibitors, tends to form amyloid fibrils under relatively mild conditions, which is why it is used as a model protein to study amyloid fibrillation. Here, we show for the first time that bundles of amyloid fibrils, i.e., helically...

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Bibliographic Details
Main Authors: Matjaž Žganec, Ajda Taler Verčič, Igor Muševič, Miha Škarabot, Eva Žerovnik
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
nano-sized object
bundle of amyloid fibrils
birefringence
intrinsic fluorescence
label-free imaging
Online Access:https://www.mdpi.com/1422-0067/24/4/3737

Internet

https://www.mdpi.com/1422-0067/24/4/3737

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