Longitudinal tracking of human fetal cells labeled with super paramagnetic iron oxide nanoparticles in the brain of mice with motor neuron disease.

Stem Cell (SC) therapy is one of the most promising approaches for the treatment of Amyotrophic Lateral Sclerosis (ALS). Here we employed Super Paramagnetic Iron Oxide nanoparticles (SPIOn) and Hoechst 33258 to track human Amniotic Fluid Cells (hAFCs) after transplantation in the lateral ventricles...

Full description

Bibliographic Details
Main Authors: Paolo Bigini, Valentina Diana, Sara Barbera, Elena Fumagalli, Edoardo Micotti, Leopoldo Sitia, Alessandra Paladini, Cinzia Bisighini, Laura De Grada, Laura Coloca, Laura Colombo, Pina Manca, Patrizia Bossolasco, Francesca Malvestiti, Fabio Fiordaliso, Gianluigi Forloni, Massimo Morbidelli, Mario Salmona, Daniela Giardino, Tiziana Mennini, Davide Moscatelli, Vincenzo Silani, Lidia Cova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3288077?pdf=render