Identification of Crucial Gene Modules Related to the Efficiency of Anti-PD-1/PD-L1 Therapy and Comprehensive Analyses of a Novel Signature Based on These Modules

Identification of Crucial Gene Modules Related to the Efficiency of Anti-PD-1/PD-L1 Therapy and Comprehensive Analyses of a Novel Signature Based on These Modules

Biomarker development for clinical checkpoint inhibition is still in its early stages. It is critical to determine the cause of the lack of a long-term response in patients after immune checkpoint blockade (ICB) treatment and to develop composite biomarkers or signatures to improve personalized appr...

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Bibliographic Details
Main Authors: Wei Wang, Dong Dong, Liang Chen, Heng Wang, Bo Bi, Tianyi Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Genetics
Subjects:
melanoma
TCGA
signature
immunotherapy
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.893380/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.893380/full

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