GAS5-inhibited hepatocyte pyroptosis contributes to hepatic stellate cell inactivation via microRNA-684 and AHR

Summary: Hepatocyte pyroptosis has been shown to be involved in liver damage progression. Previously, we found that growth arrest-specific 5 (GAS5) is a regulator of hepatic stellate cell (HSC) activation. However, whether GAS5 plays a role in hepatocyte pyroptosis remains unclear. In this study, re...

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Bibliographic Details
Main Authors: Zhichao Lang, Rongrong Zhang, Xinmiao Li, Yan Jin, Yuhang Hu, Xinyi Lin, Yunzhi Tang, Jingnan Zhang, Lei Zheng, Zhixian Yu, Jianjian Zheng
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223014037