Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial–mesenchymal transition

KIAA1199, a major glycosaminoglycan component of the extracellular matrix, was reported to induce a fibrosis-like process. However, the relationship between KIAA1199 and liver fibrosis remains unclear. The liver fibrosis mouse model was established with carbon tetrachloride (CCl4). Here, we found th...

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Bibliographic Details
Main Authors: Liu Jingmei, Xia Suhong, Han Ping, Zhang Mingyu, Wu Jingwen, Liao Jiazhi
Format: Article
Language:English
Published: De Gruyter 2023-04-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2023-0689