Hepatic stellate cells limit hepatocellular carcinoma progression through the orphan receptor endosialin

Abstract Hepatocellular carcinoma (HCC) is among the most common and deadliest cancers worldwide. A major contributor to HCC progression is the cross talk between tumor cells and the surrounding stroma including activated hepatic stellate cells (HSC). Activation of HSC during liver damage leads to u...

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Bibliographic Details
Main Authors: Carolin Mogler, Courtney König, Matthias Wieland, Anja Runge, Eva Besemfelder, Dorde Komljenovic, Thomas Longerich, Peter Schirmacher, Hellmut G Augustin
Format: Article
Language:English
Published: Springer Nature 2017-04-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.201607222