Vaccination with Leishmania infantum acidic ribosomal P0 but not with nucleosomal histones proteins controls Leishmania infantum infection in hamsters.

BACKGROUND: Several intracellular Leishmania antigens have been identified in order to find a potential vaccine capable of conferring long lasting protection against Leishmania infection. Histones and Acid Ribosomal proteins are already known to induce an effective immune response and have successfu...

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Main Authors: Lais Pereira, Melissa Abbehusen, Clarissa Teixeira, Jurema Cunha, Ivan P Nascimento, Kyioshi Fukutani, Washington dos-Santos, Aldina Barral, Camila Indiani de Oliveira, Manoel Barral-Netto, Manoel Soto, Cláudia Ida Brodskyn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4313940?pdf=render