Anticancer potential of Spirastrella pachyspira (marine sponge) against SK-BR-3 human breast cancer cell line and in silico analysis of its bioactive molecule sphingosine

Anticancer potential of Spirastrella pachyspira (marine sponge) against SK-BR-3 human breast cancer cell line and in silico analysis of its bioactive molecule sphingosine

The rate of breast cancer is rapidly increasing and discovering medications with therapeutic effects play a significant role in women’s health. Drugs derived from marine sponges have recently received FDA approval for the treatment of malignant tumors, including metastatic breast cancer. Spirastrell...

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Bibliographic Details
Main Authors: Shabna Roupal Morais, Chitra K, Srikanth Jeyabalan, Ling Shing Wong, Mahendran Sekar, Kumarappan Chidambaram, Siew Hua Gan, M. Yasmin Begum, Nur Najihah Izzati Mat Rani, Vetriselvan Subramaniyan, Shivkanya Fuloria, Neeraj Kumar Fuloria, Sher Zaman Safi, Kathiresan V. Sathasivam, Siddharthan Selvaraj, Vipin Kumar Sharma
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Marine Science
Subjects:
breast cancer
Spirastrella pachyspira
SK-BR-3 cell lines
molecular docking
HER2
anticancer
Online Access:https://www.frontiersin.org/articles/10.3389/fmars.2022.950880/full

Internet

https://www.frontiersin.org/articles/10.3389/fmars.2022.950880/full

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