Optimized Liposomal Delivery of Bortezomib for Advancing Treatment of Multiple Myeloma

Optimized Liposomal Delivery of Bortezomib for Advancing Treatment of Multiple Myeloma

Bortezomib (BTZ), a boronic acid-derived proteasome inhibitor, is commonly employed in treating multiple myeloma (MM). However, the applications of BTZ are limited due to its poor stability and low bioavailability. Herein, we develop an optimized liposomal formulation of BTZ (L-BTZ) by employing a r...

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Bibliographic Details
Main Authors: Chi Zhang, Jimmy Chun-Tien Kuo, Yirui Huang, Yingwen Hu, Lan Deng, Bryant C. Yung, Xiaobin Zhao, Zhongkun Zhang, Junjie Pan, Yifan Ma, Robert J. Lee
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceutics
Subjects:
Bortezomib
liposome
remote-loading
multiple myeloma
Tiron
Online Access:https://www.mdpi.com/1999-4923/15/12/2674

Internet

https://www.mdpi.com/1999-4923/15/12/2674

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