Dendritic cell ICAM-1 strengthens synapses with CD8 T cells but is not required for their early differentiation

Dendritic cell ICAM-1 strengthens synapses with CD8 T cells but is not required for their early differentiation

Summary: Lymphocyte priming in lymph nodes (LNs) was postulated to depend on the formation of stable T cell receptor (TCR)-specific immune synapses (ISs) with antigen (Ag)-presenting dendritic cells (DCs). The high-affinity LFA-1 ligand ICAM-1 was implicated in different ISs studied in vitro. We dis...

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Bibliographic Details
Main Authors: Anita Sapoznikov, Stav Kozlovski, Nehora Levi, Sara W. Feigelson, Ofer Regev, Natalia Davidzohn, Shifra Ben-Dor, Rebecca Haffner-Krausz, Ester Feldmesser, Noa Wigoda, Ekaterina Petrovich-Kopitman, Moshe Biton, Ronen Alon
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723008756

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http://www.sciencedirect.com/science/article/pii/S2211124723008756

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