Nobiletin alleviates atherosclerosis by inhibiting lipid uptake via the PPARG/CD36 pathway

Nobiletin alleviates atherosclerosis by inhibiting lipid uptake via the PPARG/CD36 pathway

Abstract Background Atherosclerosis (AS) is a persistent inflammatory condition triggered and exacerbated by several factors including lipid accumulation, endothelial dysfunction and macrophages infiltration. Nobiletin (NOB) has been reported to alleviate atherosclerosis; however, the underlying mec...

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Bibliographic Details
Main Authors: Heng Wang, Qinqin Tian, Ruijing Zhang, Qiujing Du, Jie Hu, Tingting Gao, Siqi Gao, Keyi Fan, Xing Cheng, Sheng Yan, Guoping Zheng, Honglin Dong
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Lipids in Health and Disease
Subjects:
Atherosclerosis
Nobiletin
Network pharmacology
PPARG/CD36 pathway
Macrophagocyte
Inflammation
Online Access:https://doi.org/10.1186/s12944-024-02049-5

Internet

https://doi.org/10.1186/s12944-024-02049-5

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