A Novel Model of Cancer Drug Resistance: Oncosomal Release of Cytotoxic and Antibody-Based Drugs

Extracellular vesicles (EVs), such as exosomes or oncosomes, often carry oncogenic molecules derived from tumor cells. In addition, accumulating evidence indicates that tumor cells can eject anti-cancer drugs such as chemotherapeutics and targeted drugs within EVs, a novel mechanism of drug resistan...

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Bibliographic Details
Main Authors: Takanori Eguchi, Eman Ahmed Taha, Stuart K. Calderwood, Kisho Ono
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/9/3/47