Catalytic multicomponent synthesis, biological evaluation, molecular docking and in silico ADMET studies of some novel 3-alkyl indoles

Catalytic multicomponent synthesis, biological evaluation, molecular docking and in silico ADMET studies of some novel 3-alkyl indoles

A series of novel 3-alkylated indoles were synthesized in good yields under mild reaction conditions using inexpensive, readily available, and environmentally benign glycolic acid catalyst. This new catalytic multicomponent reaction is attractive for diversity-oriented synthesis involving C–C bond f...

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Bibliographic Details
Main Authors: Rajalakshmi Ramarajan, Arulraj Ramalingam, Chinnaraja Duraisamy, Sivakumar Sambandam, Noureddine ISSAOUI, Omar M. Al-Dossary, Leda G. Bousiakoug
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Journal of King Saud University: Science
Subjects:
3-Alkylated indoles
Multicomponent reaction
Antimicrobial studies
Molecular docking
In silico ADMET
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364722006565

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http://www.sciencedirect.com/science/article/pii/S1018364722006565

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