Liver regeneration after extensive hepatectomy in rats: effect of preoperative chemotherapy with intravenous 5-fluorouracil

ABSTRACT Purpose: To evaluate the effect of preoperative intravenous chemotherapy with 5-fluorouracil on liver regeneration in an experimental model of major hepatectomy in rats. Methods: Wistar rats were divided into two groups of 20 animals each and submitted to 70% hepatectomy 24 h after intrav...

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Bibliographic Details
Main Authors: Marciano Anghinoni, Edimar Leandro Toderke, Thaísa Sami Nakadomari, Tiago Kuchnir Martins de Oliveira, Felipe Pedrotti Locatelli, Jorge Eduardo Fouto Matias
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2022-11-01
Series:Acta Cirúrgica Brasileira
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502022000900200&tlng=en