Catastrophic Collision Between Obesity and COVID-19 Have Evoked the Computational Chemistry for Research in Silico Design of New CaMKKII Inhibitors Against Obesity by Using 3D-QSAR, Molecular Docking, and ADMET

Catastrophic Collision Between Obesity and COVID-19 Have Evoked the Computational Chemistry for Research in Silico Design of New CaMKKII Inhibitors Against Obesity by Using 3D-QSAR, Molecular Docking, and ADMET

The purpose of the paper is to discuss the various methods and computational approaches, which are used in computer-aided drug design. For this reason, pyrimidine and azaindole derivatives have been used to study the inhibitory activity of CaMKKII. It is an enzyme that enters the brain to greatly...

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Bibliographic Details
Main Authors: Halima Hajji, Fatima En-nahli, Ilham Aanouz, Hanane Zaki, Tahar Lakhlifi, Mohammed Aziz Ajana, Mohammed Bouachrine
Format: Article
Language:English
Published: Universidade Federal de Mato Grosso do Sul 2021-10-01
Series:Orbital: The Electronic Journal of Chemistry
Subjects:
3D-QSAR; ADMET; CaMKKII inhibitors; Molecular Docking; Obesity
Online Access:https://periodicos.ufms.br/index.php/orbital/article/view/15579

Internet

https://periodicos.ufms.br/index.php/orbital/article/view/15579

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