Synthesis and evaluation of N-isopropyl-p-[11C]methylamphetamine as a novel cerebral blood flow tracer for positron emission tomography

Synthesis and evaluation of N-isopropyl-p-[11C]methylamphetamine as a novel cerebral blood flow tracer for positron emission tomography

Abstract Introduction Increases in fasting plasma glucose (PG) levels lead to a decrease in 2-deoxy-2-[18F]fluoro-d-glucose ([18F]FDG) uptake in the normal brain, especially in the precuneus, resulting in an Alzheimer’s disease (AD)-like uptake pattern. Therefore, patients with higher PG levels, suc...

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Bibliographic Details
Main Authors: Jun Toyohara, Norihiro Harada, Takeharu Kakiuchi, Hiroyuki Ohba, Masakatsu Kanazawa, Tetsuro Tago, Muneyuki Sakata, Kiichi Ishiwata
Format: Article
Language:English
Published: SpringerOpen 2020-10-01
Series:EJNMMI Research
Subjects:
Phenylalkylamine
Cerebral blood flow
Positron emission tomography
Non-human primate
Carbon-11
Online Access:http://link.springer.com/article/10.1186/s13550-020-00702-5

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http://link.springer.com/article/10.1186/s13550-020-00702-5

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