Lichen Secondary Metabolites Inhibit the Wnt/β-Catenin Pathway in Glioblastoma Cells and Improve the Anticancer Effects of Temozolomide

Lichen Secondary Metabolites Inhibit the Wnt/β-Catenin Pathway in Glioblastoma Cells and Improve the Anticancer Effects of Temozolomide

Lichens are a source of secondary metabolites with significant pharmacological potential. Data regarding their possible application in glioblastoma (GBM) treatment are, however, scarce. The study aimed at analyzing the mechanism of action of six lichen secondary metabolites: atranorin, caperatic aci...

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Bibliographic Details
Main Authors: Aleksandra Majchrzak-Celińska, Robert Kleszcz, Elżbieta Studzińska-Sroka, Agnieszka Łukaszyk, Anna Szoszkiewicz, Ewelina Stelcer, Karol Jopek, Marcin Rucinski, Judyta Cielecka-Piontek, Violetta Krajka-Kuźniak
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
lichen secondary metabolites
glioblastoma
Wnt/β-catenin pathway
caperatic acid
physodic acid
temozolomide
Online Access:https://www.mdpi.com/2073-4409/11/7/1084

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https://www.mdpi.com/2073-4409/11/7/1084

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