Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis
Abstract The glutathione (GSH) system is considered to be one of the most powerful endogenous antioxidant systems in the cardiovascular system due to its key contribution to detoxifying xenobiotics and scavenging overreactive oxygen species (ROS). Numerous investigations have suggested that disrupti...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-02-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-05645-y |