Development and application of the direct mycobacterial growth inhibition assay: a systematic review

IntroductionFirst described by Wallis et al. in 2001 for the assessment of TB drugs, the direct mycobacterial growth inhibition assay (MGIA) offers a tractable ex vivo tool measuring the combined influences of host immunity, strain virulence and intervention effects. Over the past 13 years, we have...

Full description

Bibliographic Details
Main Authors: Hannah Painter, Eli Harriss, Helen A. Fletcher, Helen McShane, Rachel Tanner
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1355983/full