In Silico Screening of Quorum Sensing Inhibitor Candidates Obtained by Chemical Similarity Search

Quorum sensing (QS) is a bacterial communication using signal molecules, by which they sense population density of their own species, leading to group behavior such as biofilm formation and virulence. Autoinducer-2 (AI2) is a QS signal molecule universally used by both gram-positive and gram-negativ...

Full description

Bibliographic Details
Main Authors: Sharath Belenahalli Shekarappa, Hrvoje Rimac, Julian Lee
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/15/4887