Expression and splicing mediate distinct biological signals

Expression and splicing mediate distinct biological signals

Abstract Background Through alternative splicing, most human genes produce multiple isoforms in a cell-, tissue-, and disease-specific manner. Numerous studies show that alternative splicing is essential for development, diseases, and their treatments. Despite these important examples, the extent an...

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Bibliographic Details
Main Authors: Søren Helweg Dam, Lars Rønn Olsen, Kristoffer Vitting-Seerup
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Biology
Subjects:
Alternative splicing
Isoform
Isoform expression
Gene expression
RNA-sequencing
RNA-seq
Online Access:https://doi.org/10.1186/s12915-023-01724-w

Internet

https://doi.org/10.1186/s12915-023-01724-w

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