In silico estrogen receptor alpha antagonist studies and toxicity prediction of Melia azedarach leaves bioactive ethyl acetate fraction

The estrogen hormone dependent accounts for a major cause in the incidence of women breast cancer. Thus, their receptor, especially the estrogen receptor α (ER-α), is becoming a target in endocrine treatment. These ligand-inducible nuclear functions are regulated by an array of phytochemical and syn...

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Bibliographic Details
Main Authors: Martha Ervina, Mohammad Rizki Fadhil Pratama, Hadi Poerwono, Juni Ekowati, Retno Widyowati, Katsuyoshi Matsunami, Sukardiman
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2021;volume=12;issue=3;spage=236;epage=241;aulast=Ervina