Comparative Hepatotoxicity of Fluconazole, Ketoconazole, Itraconazole, Terbinafine, and Griseofulvin in Rats

Oral ketoconazole was recently the subject of regulatory safety warnings because of its association with increased risk of inducing hepatic injury. However, the relative hepatotoxicity of antifungal agents has not been clearly established. The aim of this study was to compare the hepatotoxicity indu...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Star Khoza, Ishmael Moyo, Denver Ncube
Format: Artikel
Sprache:English
Veröffentlicht: Hindawi Limited 2017-01-01
Schriftenreihe:Journal of Toxicology
Online Zugang:http://dx.doi.org/10.1155/2017/6746989