Firing Alterations of Neurons in Alzheimer’s Disease: Are They Merely a Consequence of Pathogenesis or a Pivotal Component of Disease Progression?

Firing Alterations of Neurons in Alzheimer’s Disease: Are They Merely a Consequence of Pathogenesis or a Pivotal Component of Disease Progression?

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder, yet its underlying causes remain elusive. The conventional perspective on disease pathogenesis attributes alterations in neuronal excitability to molecular changes resulting in synaptic dysfunction. Early hyperexcitability is...

Full description

Bibliographic Details
Main Authors: Nikolaos P. Tzavellas, Konstantinos I. Tsamis, Andreas P. Katsenos, Athena S. Davri, Yannis V. Simos, Ilias P. Nikas, Stefanos Bellos, Panagiotis Lekkas, Foivos S. Kanellos, Spyridon Konitsiotis, Charalampos Labrakakis, Patra Vezyraki, Dimitrios Peschos
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cells
Subjects:
Alzheimer’s disease
neurophysiology
pyramidal neurons
interneurons
LTP
dendritic spine
Online Access:https://www.mdpi.com/2073-4409/13/5/434

Internet

https://www.mdpi.com/2073-4409/13/5/434

Similar Items