The conserved SKN-1/Nrf2 stress response pathway regulates synaptic function in Caenorhabditis elegans.

The conserved SKN-1/Nrf2 stress response pathway regulates synaptic function in Caenorhabditis elegans.

The Nrf family of transcription factors plays a critical role in mediating adaptive responses to cellular stress and defends against neurodegeneration, aging, and cancer. Here, we report a novel role for the Caenorhabditis elegans Nrf homolog SKN-1 in regulating synaptic transmission at neuromuscula...

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Bibliographic Details
Main Authors: Trisha A Staab, Trevor C Griffen, Connor Corcoran, Oleg Evgrafov, James A Knowles, Derek Sieburth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3605294?pdf=render

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http://europepmc.org/articles/PMC3605294?pdf=render

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