Human Claudin-8 and -14 Are Receptors Capable of Conveying the Cytotoxic Effects of <named-content content-type="genus-species">Clostridium perfringens</named-content> Enterotoxin

ABSTRACT Clostridium perfringens enterotoxin (CPE) contributes to several important human gastrointestinal (GI) diseases. This toxin and its derivatives are also being explored for translational applications, i.e., cancer therapy or drug delivery. Some, but not all, members of the 24-member claudin...

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Bibliographic Details
Main Authors: Archana Shrestha, Bruce A. McClane
Format: Article
Language:English
Published: American Society for Microbiology 2013-03-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00594-12