Metabolic study of trimetazidine using ultra-high performance liquid chromatography-tandem mass spectrometry

Metabolic study of trimetazidine using ultra-high performance liquid chromatography-tandem mass spectrometry

Abstract In the present study, the application of ultra-high performance liquid chromatography-tandem mass spectrometry allowed us to study of known-as well as hitherto unknown-trimetazidine (TMZ) metabolites in human urine and to propose their renal excretion profiles. Urine samples from a healthy...

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Bibliographic Details
Main Authors: Kamila Chomaničová, Élida Alechaga Silva, Rosa Ventura Alemany
Format: Article
Language:English
Published: Universidade de São Paulo 2023-05-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Trimetazidine
Liquid chromatography
Mass spectrometry
Excretion profiles
Metabolites
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502023000100362&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502023000100362&lng=en&tlng=en

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