CXCR2 intrinsically drives the maturation and function of neutrophils in mice

Neutrophils play a major role in the protection from infections but also in inflammation related to tumor microenvironment. However, cell-extrinsic and -intrinsic cues driving their function at steady state is still fragmentary. Using Cxcr2 knock-out mice, we have evaluated the function of the chemo...

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Bibliographic Details
Main Authors: Pauline Delobel, Benjamin Ginter, Eliane Rubio, Karl Balabanian, Gwendal Lazennec
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1005551/full